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	Nano.Cancer.Gov News - July 2009


	Implantable Device Offers Continuous Cancer Monitoring Surgical removal of a tissue sample is now the standard for diagnosing cancer. [ read more ] Nanoparticles Image Breast Cancer Current methods of detecting breast cancer suffer from low sensitivity, limited spatial resolution, or the need to use complicated and expensive radioisotope-based technologies. [ read more ] Targeted Nanoparticles Boost Arsenic's Anticancer Punch Arsenic trioxide has a long history as a potent human poison, but it also has proven valuable as one of the primary treatment options for acute promyelocytic leukemia. [ read more ] Nanoparticle-Based "Chemical Nose” Sniffs Out Cancer Earlier To Improve Treatment Options Using a "chemical nose” array of nanoparticles and polymers, researchers at the University of Massachusetts Amherst have developed a fundamentally new, more effective way to differentiate not only between healthy and cancerous cells but also between metastatic and nonmetastatic cancer cells. [ read more ] Monitoring Cancer Cell Changes With Quantum Dots One of the earliest events that changes a normal cell into a malignant one is known as deoxyribonucleic acid (DNA) hypermethylation, a biochemical alteration that inactivates critical tumor-suppressor genes. [ read more ] New Nanoparticles Could Revolutionize Therapeutic Drug Discovery Understanding the structure of proteins is a vital first step in developing new drugs, but to date, researchers have had difficulty studying the large number of proteins that are normally embedded in the cell membrane, a family of proteins that includes those involved in cancer-related signaling processes. [ read more ]

SOURCE: NanoNews-Now Digest

New NIH Funding to Support UAB Total Joint Replacement Research Collaboration
University of Alabama at Birmingham (UAB) July 19th, 2009 Newly announced National Institutes of Health (NIH) funding will expand the reach of ongoing University of Alabama at Birmingham (UAB) research into a unique nanostructured coating to improve the performance and longevity of total joint replacement components. The broadened UAB research opportunity is funded by a four-year, $790,931 National Institutes of Health (NIH) grant through the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS).

Micro Nano Breakthrough Conference (MNBC) & Oregon Built Environment & Sustainable Technologies Center (Oregon BEST) presents Solar Materials Symposium Monday, September 21, 2009
ONAMI July 20th, 2009 The 6th annual Micro Nano Breakthrough Conference (Portland, OR; September 21-23, 2009 www.micronbc.org) and Oregon BEST (oregonbest.org) are pleased to announce a full-day Solar Materials Symposium as a new short-course option this year.

California's Channel Islands hold evidence of Clovis-age comets
University of Oregon July 20th, 2009 University of Oregon-led research team digs up strongest evidence yet for a controversial cosmic event

Muscular protein bond -- strongest yet found in nature
Technische Universitaet Muenchen July 20th, 2009 Single-molecule experiments show how mechanical strength in muscles is anchored in the titin-telethonin complex

Berkeley Lab Wins Four 2009 R&D R&D 100 Awards
Berkeley Lab July 20th, 2009 Berkeley Lab won four of R&D Magazine's R&D 100 Awards for 2009, which recognize the 100 most significant proven technological advances of the year. This year's winners offer the promise of cost-competitive solar cells, more computer memory at less cost, an unmatched look at atomic scale matter in 3-D, and a more powerful way to find hidden energy sources.

Carbon:Life's most important element
bangkokpost.com July 20th, 2009 Anything living (or dead, for that matter) contains carbon, as does the fuel for cars and motorbikes, all plastics and even wax candles and lightweight carbon fibres. Carbon is simply omnipresent. Graphite is also the only non-metal that conducts electricity. This is because the extra electron that isn't used in bonding, due to only bonding to three other carbons, can now move within the graphite and allows electricity to flow. There are many other allotropes of carbon, including the fullerenes, but their applications are still under research, although there may be cancer cures and applications in nanotechnology, so researchers are continuously finding new ways to use carbon.

Nanoscience Saves Lives
weau.com July 20th, 2009 Every day, researchers get closer to possibly curing diseases like diabetes and multiple sclerosis. And instructors in nanoscience at CVTC are conducting experiments that directly relate to curing these diseases. These instructors say Wisconsin is one of the top three centers in the United States for nanosciene research -- and they are excited about the applications of their research in helping save peoples lives. CVTC nanoscience instructors John Wagner and Hans Mikelson say the ability to help people is at the core of why they do their work. Wagner says, "The ability to help mankind, apply high technology and actually help man solve some of the problems that are associated with normal life."

Super tiny technology could power superfast airplanes
Princeton July 20th, 2009 Supersonic aircraft may get a boost in speed from the tiniest of manmade particles

Tension in axons is essential for synaptic signaling, researchers report
University of Illinois July 20th, 2009 Every time a neuron sends a signal - to move a muscle or form a memory, for example - tiny membrane-bound compartments, called vesicles, dump neurotransmitters into the synapse between the cells. Researchers report that this process, which is fundamental to the workings of the nervous system, relies on a simple mechanical reality: Tension in the axon of the presynaptic neuron is required.

QuantaSol unveils 28.3% efficient single-junction solar cell World Record
QuantaSol July 21st, 2009 QuantaSol unveils 28.3% efficient single-junction solar cell World record made public at UK's Royal Society Summer Science Exhibition

It’s the small stuff that matters
Oak Ridge National Laboratory July 21st, 2009 To understand transformations of matter, scientists at DOE's Pacific Northwest National Laboratory aided in developing methods to determine how fast clusters of molecules form and their corresponding stability.

Chasing tiny vehicles
Ludwig-Maximilians-Universität July 21st, 2009 Microscope shows how nanoferries invade cells

Implantable Device Offers Continuous Cancer Monitoring
NCI Alliance for Nanotechnology in Cancer July 21st, 2009 Surgical removal of a tissue sample is now the standard for diagnosing cancer. Such procedures, known as biopsies, are accurate but offer only a snapshot of the tumor at a single moment in time.

Nanoparticles Image Breast Cancer
NCI Alliance for Nanotechnology in Cancer July 21st, 2009 Current methods of detecting breast cancer suffer from low sensitivity, limited spatial resolution, or the need to use complicated and expensive radioisotope-based technologies.

Targeted Nanoparticles Boost Arsenic’s Anticancer Punch
NCI Alliance for Nanotechnology in Cancer July 21st, 2009 Arsenic trioxide has a long history as a potent human poison, but it also has proven valuable as one of the primary treatment options for acute promyelocytic leukemia. Efforts to use arsenic trioxide to treat other types of cancer are under way, but clinical trials are revealing that the extreme toxicity of this material is likely to limit its utility as a broad-spectrum anticancer agent.

Nanoparticle-Based "Chemical Nose" Sniffs Out Cancer Earlier To Improve Treatment Options
NCI Alliance for Nanotechnology in Cancer July 21st, 2009 Using a "chemical nose" array of nanoparticles and polymers, researchers at the University of Massachusetts Amherst have developed a fundamentally new, more effective way to differentiate not only between healthy and cancerous cells but also between metastatic and nonmetastatic cancer cells. It is a tool that could revolutionize cancer detection and treatment, according to Vincent M. Rotello, Ph.D., M.Phil., and D. Joseph Jerry, Ph.D., M.S., the investigators who led the study.

Monitoring Cancer Cell Changes With Quantum Dots
NCI Alliance for Nanotechnology in Cancer July 21st, 2009 One of the earliest events that changes a normal cell into a malignant one is known as deoxyribonucleic acid (DNA) hypermethylation, a biochemical alteration that inactivates critical tumor-suppressor genes. A team of investigators at Johns Hopkins University has developed a quantum dot-based method that can quantify DNA methylation in premalignant cells harvested from human patients.

New Nanoparticles Could Revolutionize Therapeutic Drug Discovery
NCI Alliance for Nanotechnology in Cancer July 21st, 2009 Understanding the structure of proteins is a vital first step in developing new drugs, but to date, researchers have had difficulty studying the large number of proteins that are normally embedded in the cell membrane, a family of proteins that includes those involved in cancer-related signaling processes. However, using nanoparticles, scientists from the University of Birmingham in the United Kingdom have found a way to preserve membrane proteins intact, enabling detailed analysis of their structure, molecular functions, and interaction with potential anticancer agents.

Energenics Placement and Product Order
Antaria Limited July 21st, 2009 Antaria Limited today announced it had reached an agreement with its strategic partner Energenics Holdings Pte Ltd of Singapore that will see Antaria increase its working capital reserves by an amount in excess of A$1.5 million and allows Energenics to have additional resources to continue with its own business development.

Leti and MAPPER launch IMAGINE Program with Delivery of MAPPER's Massively Parallel Electron Beam Platform
CEA-Leti July 21st, 2009 CEA-Leti and MAPPER Lithography announce today that MAPPER has delivered one of its massively parallel electron beam platforms to CEA-Leti

Twinkling nanostars cast new light into biomedical imaging
Purdue University July 21st, 2009 Purdue University researchers have created magnetically responsive gold nanostars that may offer a new approach to biomedical imaging

Nanotechnology strategy
theengineer.co.uk July 21st, 2009 Lord Drayson, the UK science and innovation minister and chair of the Ministerial Group on Nanotechnologies, has called on industry to get involved in shaping a UK strategy for nanotechnologies. Industry, academia and consumer groups have been invited to use a new website at www.interactive.bis.gov.uk/nano to help develop the strategy, building on existing research that has already taken place.

Low Noise Top Gate Graphene Transistor is Demonstrated
University of California - Riverside July 22nd, 2009 Graphene, which consists of just a single atomic layer of carbon atoms bound into crystal lattice, is the hottest new material system considered for applications in future electronics and sensors. The properties, which make graphene so desirable for future electronics, are its extremely high electrical and thermal conductivities. For any transistor to be useful for communications or information processing, the level of the electronic low-frequency noise (also referred to as 1/f or flicker noise) has to be reduced to an acceptable level defined by the Hooge parameter. Although modern electronic devices such as cell phones and radars operate at very higher frequencies (GHz range), the low-frequency 1/f noise is extremely important. Due to unavoidable non-linearities in devices and systems, the low frequency noise up-converts to higher requencies, and contributes to the phase noise of the system, thus limiting its performance. The same is true for the proposed applications of graphene as a material for ultra-sensitive detectors.

Purer water made possible by Sandia advance: A single atom makes a big difference
Sandia National Laboratories July 22nd, 2009 By substituting a single atom in a molecule widely used to purify water, researchers at Sandia National Laboratories have created a far more effective decontaminant with a shelf life superior to products currently on the market. Sandia has applied for a patent on the material, which removes bacterial, viral and other organic and inorganic contaminants from river water destined for human consumption, and from wastewater treatment plants prior to returning water to the environment.

More Than Meets the Eye: New Blue Light Nanocrystals
Berkeley Lab July 22nd, 2009 Berkeley Lab researchers have produced non-toxic magnesium oxide nanocrystals that efficiently emit blue light and could also play a role in long-term storage of carbon dioxide, a potential means of tempering the effects of global warming.

NIST Awards $55.5 Million in Grants for New University Research Facilities
NIST July 22nd, 2009 The U.S. Commerce Department's National Institute of Standards and Technology (NIST) announced today that it is awarding grants totaling more than $55.5 million to four universities to provide cost-shared support for the construction of new scientific research facilities. "These awards mean four major construction projects in these local areas, with the jobs and economic benefits they bring," U.S. Commerce Secretary Gary Locke said, "but even more important, these four projects provide a major boost to scientific research at four respected universities, enhancing innovation, public safety and environmental protection for many, many years to come."

In Pursuit of Immortality: The science behind life extension
familyhealthguide.co.uk July 22nd, 2009 Since the beginning of recorded history, humans have searched for the key to immortality and eternal youth. From the epic of Gilgamesh, recorded on clay tablets around 2000 B.C., to Ponce de Leon's famed search for the fountain of youth in the new world, the extension of life has been a recurring theme for humanity. Today, scientists are coming closer than ever to making real medical breakthroughs that will "cure" aging and eventually bring an end to natural death. Pharmaceutical discoveries, and advances in the fields of nanotechnology, cloning, stem cell research and cryonics offer tantalizing glimpses at a future free from old age, and the ability to actually reverse the aging process itself - possibilities that life extension experts feel could become a reality by 2019. Of course, along with these discoveries come ethical questions about the meaning of life in the absence of death and the fate of religion, as well as concerns about overpopulation, boredom and why anyone would really want to live forever. If the claims of life extension proponents sound far fetched, consider the fact that the average human lifespan has doubled since 1900 and continues to increase. Enormous medical advances occurred during the 20th century, resulting in the development of medications and technology that were once unthinkable. Less than 100 years ago, insulin was unknown and type 1 diabetes was a fatal and mysterious disease. Now, insulin is an inexpensive and easily obtainable drug that saves lives every day. Other medical devices that are common today, like internal pacemakers and contact lenses, were unthinkable just 100 years ago, and the rate of medical and scientific advances continues to increase.

Can you see ahead 90 years?
ieet.org July 22nd, 2009 Give us your best guess about the state of the world in the year 2099. We've posted a new IEET poll, asking our readers to look ahead nine decades and try to make an informed guess about what the world will look like at the end of this century. Here are the options from which you can choose (multiple answers are accepted, and you can also "write in" your own statement): * Utopia! A post-scarcity society basking in freedom and prosperity. * Posthumans will dominate, with unenhanced humans a tiny minority. * Considerable off-Earth expansion, enabled by nanotech and biotech. * Ups and downs along the way, but overall about the same. * Much worse than today due to climate chaos and environmental collapse. * Near or total destruction of civilization from all-out warfare. * Humanity enslaved by a totalitarian global government. * Superintelligent AI will usher in a Singularity and all bets are off. * Other. So, what do you think we can expect?

New windows opened on cell-to-cell interactions: Oregon researcher puts new focus on how particles of colloidal materials and artificial cells interact
University of Oregon July 22nd, 2009 Applying biological molecules from cell membranes to the surfaces of artificial materials is opening peepholes on the very basics of cell-to-cell interaction. Two recently published papers by a University of Oregon biophysicist and colleagues suggest that putting lipids and other cell membrane components on manufactured surfaces could lead to new classes of self-assembling materials for use in precision optics, nanotechnology, electronics and pharmaceuticals.

Caltech Physicists Create First Nanoscale Mass Spectrometer: Device can instantly measure the mass of an individual molecule
Caltech July 22nd, 2009 Using devices millionths of a meter in size, physicists at the California Institute of Technology (Caltech) have developed a technique to determine the mass of a single molecule, in real time. The mass of molecules is traditionally measured using mass spectrometry, in which samples consisting of tens of thousands of molecules are ionized, to produce charged versions of the molecules, or ions. Those ions are then directed into an electric field, where their motion, which is choreographed by both their mass and their charge, allows the determination of their so-called mass-to-charge ratio. From this, their mass can ultimately be ascertained.

Coffee Drinkers, Say Hello to Scald-Proof Nanofabric
popsci.com July 23rd, 2009 With scalding liquids, however, problems set in: not only do they cause the waxy coating to melt, but hot water also drives away the air. What's more, hot water drops are able to make their way into smaller nooks in the surface. Classically water-resistant surfaces, like the leaves above, succumb to hot water, letting it ooze through without resistance. Well aware of the above research, as well as of recent studies pointing to the water-resilient properties of carbon nanotubes, the team of chemists at the University of Minnesota created a cocktail of carbon nanotubes, Teflon, and cotton fabric. This fabric successfully repels hot water, milk, coffee, and tea at 167 °F.

Vaccine Patch Nano-Pinpoints Flu Inoculation
popsci.com July 23rd, 2009 After yesterday's announcements by the World Health Organization, calling swine flu "unstoppable" and noting that there might not be enough vaccine produced by the time flu season rolls around, the debate began over what to do with the small amount of H1N1 vaccine that will be produced this year. Well, if you're Australian scientist Mark Kendall, you answer that question by designing a vaccine system that provides the same protection as a regular shot, but only uses a fraction of the vaccine.

New silver nanoparticle skin gel for healing burns
American Chemical Society July 23rd, 2009 Scientists in India are reporting successful laboratory tests of a new and potentially safer alternative to silver-based gels applied to the skin of burn patients to treat infections.

Bharatbook.com : Real economic potential & latent demand for Products Incorporating Nanotechnology
Bharat Book Bureau July 23rd, 2009 Bharatbook.com added a new "Report on Products Incorporating Nanotechnology World Market Segmentation by City" into its market report catalogue for reselling.

Oral drugs that can pack more of a punch
israel21c.org July 23rd, 2009 It may be the latest scientific trend, but Professor Simon Benita of the Hebrew University's School of Pharmacy has been working with nanotechnology since long before it had a name. His 25 years of research in nanotech has culminated in a new vehicle for oral drug delivery based on the microencapsulated double-coated nanocapsules that he developed. Normally, our bodies' defenses would stop and break down orally administered drugs, so that we only benefit from about three-quarters of their potential effectiveness. Now, thanks to P-gpBypass, Benita's invention, important cancer and HIV drugs as well as a range of immunosupressants should be able to slip through those defenses to treat disease more effectively.

EDF Energies Nouvelles (EDF EN) and First Solar, Inc. announce venture to build largest solar manufacturing plant in France
First Solar July 23rd, 2009 EDF Energies Nouvelles (EDF EN) and First Solar, Inc. (Nasdaq: FSLR) today announced a venture to build France's largest solar panel manufacturing plant.

Spain, Portugal open nanotechnology research center
reuters.com July 23rd, 2009 Spanish Prime Minister Jose Luis Rodriguez Zapatero Friday hailed the opening of a joint scientific research center with Portugal as the dawning of a new age of discovery for the two countries. Zapatero and Portuguese Prime Minister Jose Socrates were among dignitaries who attended the opening of the Iberian nanotechnology research center in northern Portugal, which is expected to attract the world's top minds in the field of submolecular research.

Nano Med Tech Advancing in FDA Approvals
live-pr.com July 23rd, 2009 Originally, Nano Med Tech contingent comprised a team of eleven Chinese Nationals, all of whom obtained doctorates in the nanotechnology field at top-tier US and UK universities. Since establishing themselves as a viable and marketable entity, they have apparently expanded to include a US-based research division. The line between todays science fact and tomorrows science fiction appears to be fading as Nano Med Tech continue to advance through widely publicized FDA approval matrix.

Nanoco Settles Patent Infringement Lawsuit with Nanosys, Inc. for Quantum Dot Technology
Nanoco July 23rd, 2009 Nanoco Technologies Ltd. today announced it has agreed to settlement terms of a patent infringement lawsuit brought by Nanosys, Inc.

Haste Makes Nano Wste
columbiacitypaper.com July 23rd, 2009 Overall, the rapidly growing nanotechnology sector promises steady job growth and seemingly endless commercial applications. The National Science Foundation has estimated the need for workers in the nanotech sector will rise from the current 20,000 to around two million in the next decade. It is expected to swell from a $200 billion industry to a $3 trillion industry in just the next five years. Yet, with this burgeoning technology also comes a growing concern -particularly from the Environmental Protection Agency and the Food and Drug Administration—about the little-known effects that waste being produced on the nano level might have on the chemical makeup of our environment. The University of South Carolina's Nanocenter, however, is spearheading research on the problem and recently received additional funding through a $3 million endowment from the state's Centers of Economic Excellence program. The university's newly minted Center for Nanoenvironmental Research and Risk Assessment will study the effect of nanomaterials on humans and the environment in a more preemptive and preventative capacity, rather than after environmental problems arise.

Inorganic Nanoscience Award To Charles Lieber
Harvard University NanoCenter July 23rd, 2009 Charles M. Lieber, Mark Hyman Jr. Professor of Chemistry at Harvard University (cmliris.harvard.edu/people/CML.php), is the winner of the 2009 Inorganic Nanoscience Award presented by the ACS Division of Inorganic Chemistry to honor excellent research. The award is sponsored by the NanoCenter of the University of South Carolina.

Rolling out the nanotubes: Synthesis of graphitic nanotubes containing platinum metals achieved through self-assembly techniques
Riken July 24th, 2009 Nanoscale materials with well-defined shapes, such as one-dimensional hollow tubes, have attracted the interest of scientists seeking to utilize their unique properties. Nanotubes have large inner and outer surface areas that are accessible to many smaller molecules, meaning they have the potential to be developed into new types of sensors and catalysts.

Luther Forest Technology campus welcomes Globalfoundries as they break ground on world’s most advanced chip fabrication plant, marking the beginning of a new era in US economic d
Luther Forest Technology Campus Economic Development Corporation (LFTC) July 24th, 2009 Project Will Bring Thousands of Jobs, Aiding the Region's Economy in the Largest Economic Development Project in the United States

Quantum dot research could lead to medical advances
Missouri University of Science and Technology July 24th, 2009 Working with atomic-scale particles known as quantum dots, a Missouri University of Science and Technology biologist hopes to develop a new and better way to deliver and monitor proteins, medicine, DNA and other molecules at the cellular level.

Molecules mean more Moore 'Silicon with afterburners' developed at Rice could be boon to electronics manufacturers
Rice University July 24th, 2009 Silicon is at the heart of an electronics revolution that has buoyed the civilized world for decades. But as time goes on and technology advances, it's becoming apparent that silicon could use a little help. A Rice University laboratory is manipulating molecules that might just be the ticket to extending Moore's Law, the theory that dictates the number of transistors that can be placed on an integrated circuit doubles about every two years.

SOURCE: NANOTECHWEB.ORG NEWSWIRE

TECHNOLOGY UPDATE

Understanding nanoscale light emission

Optical properties of nanoparticles unravelled by NREL team

http://nanotechweb.org/cws/article/tech/39864

3D nanopillars make good photovoltaics

Devices built on low-cost, flexible substrates show promising light-conversion efficiencies

http://nanotechweb.org/cws/article/tech/39848

Laser pulse transforms metal grating into nanodot array Guided laser melting cuts the cost of producing high-throughput periodic nanoarrays

http://nanotechweb.org/cws/article/tech/39824

DNA sorts carbon nanotubes

Liquid chromatography used to separate metal tubes from semiconductors

http://nanotechweb.org/cws/article/tech/39822

LAB TALK

Sponsored by 35th International Conference on Micro & Nano Engineering From 28 September to 1 October 2009, the 35th International Conference on Micro & Nano Engineering (MNE 2009, www.mne09.org) will be organized in Ghent, Belgium. This conference brings together engineers and scientists from all over the world to exchange latest breakthroughs in the fields of Micro & Nano Lithography, Fabrication, Engineering, Fabrication for Life Sciences; Systems, MEMS, NEMS.

http://www.mne09.org

Nanocomposite enhances cycling performance of lithium-ion batteries Core-shell heterostructured Fe/Fe3O4 nanocomposite offers efficient electron transport path to current collector

http://nanotechweb.org/cws/article/lab/39847

Nickel electrodes challenge ITO in OLED test Thin-film nickel anode performs well in comparative study

http://nanotechweb.org/cws/article/lab/39843

Tiny bead gathers data inside living cell Tactile exploration is made possible by closing a real-time feedback loop around a photonic-force microscope http://nanotechweb.org/cws/article/lab/39820

The 2008 ISI impact factor for Nanotechnology has risen to 3.446 http://www.iop.org/EJ/journal/Nano

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